UBQLN1 CLIA Kit for Human(Homo sapiens) | EIAab.comUBQLN1 CLIA Kit for Human(Homo sapiens)

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Index > Protein center > UBQLN1(Gene name) > Human

UBQLN1 (Gene name),

Ubiquilin-1 (Protein name ), UBQL1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

UBQLN1(DA41;PLIC1);

Protein name:

Ubiquilin-1;

Alternative:

Protein linking IAP with cytoskeleton 1(PLIC-1;hPLIC-1);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Binds CD47, NBL1, GABRA1, GABRA2, GABRA3, GABRA6, GABRB1, GABRB2 and GABRB3 (By similarity). Binds UBE3A, BTRC, P4HB, MTOR, PSEN1 and PSEN2. Interacts with the proteasome 19S subunit.

Function:

Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors (By similarity). Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation.

Subcellular Location:

Cytoplasm Nucleus

Protein Attributes:

Sequence length:

589

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

589:

LEQLSAMGFL | NREANLQALI | ATGGDINAAI | ERLLGSQPS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

605046

Pfam:

PF00627

String:

Q9UMX0

KEGG:

hsa:29979

SMR:

Q9UMX0

UniGene:

Hs.9589

STRING:

9606.ENSP00000365576

Uniprot:

Q9UMX0

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ELISA Kit for Human Ubiquilin-1

Cat.:

E9392m

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96T

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ELISA Kit for Human Ubiquilin-1

Cat.:

E9392r

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Packing:

96T

ELISA Kit for Human Ubiquilin-1

Cat.:

E9392h

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Manual:

Looking for manual.

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96T

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CLIA Kit for Human Ubiquilin-1

Cat.:

U9392r

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MSDS:

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Packing:

96T

CLIA Kit for Human Ubiquilin-1

Cat.:

U9392h

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MSDS:

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Packing:

96T

CLIA Kit for Human Ubiquilin-1

Cat.:

U9392m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Ubiquilin-1

Cat.:

P9392Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Ubiquilin-1

Cat.:

P9392Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Ubiquilin-1

Monoclonal Antibody for Human Ubiquilin-1

Protein for Human Ubiquilin-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation."
Mah A.L. , Perry G. , Smith M.A. , Monteiro M.J.
J. Cell Biol.151:847-862(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INTERACTION WITH PSEN1 AND PSEN2;TISSUE SPECIFICITY
tissue: Brain.
2.

Mah A.L. , Monteiro M.J.
Submitted (2002-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

"The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome."
Kleijnen M.F. , Shih A.H. , Zhou P. , Kumar S. , Soccio R.E. , Kedersha N.L. , Gill G. , Howley P.M.
Mol. Cell6:409-419(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INTERACTION WITH UBE3A; BTRC AND THE PROTEASOME
tissue: B-cell.
4.

"Molecular cloning and expression analysis of the human DA41 gene and its mapping to chromosome 9q21.2-q21.3."
Hanaoka E. , Ozaki T. , Ohira M. , Nakamura Y. , Suzuki M. , Takahashi E. , Moriya H. , Nakagawara A. , Sakiyama S.
J. Hum. Genet.45:188-191(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Lung.
5.

"Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs."
Wiemann S. , Weil B. , Wellenreuther R. , Gassenhuber J. , Glassl S. , Ansorge W. , Boecher M. , Bloecker H. , Bauersachs S. , Blum H. , Lauber J. , Duesterhoeft A. , Beyer A. , Koehrer K. , Strack N. , Mewes H.-W. , Ottenwaelder B. , Obermaier B. , more...
Genome Res.11:422-435(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
6.

"DNA sequence and analysis of human chromosome 9."
Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue: Brain.
tissue: Muscle.
9.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-316
tissue: Embryo.
10.

Lubec G. , Chen W.-Q. , Sun Y.
Submitted (2008-12) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 71-83; 207-236; 244-253 AND 547-582;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Fetal brain cortex.
11.

"Characterization of ubiquilin 1, an mTOR-interacting protein."
Wu S. , Mikhailov A. , Kallo-Hosein H. , Hara K. , Yonezawa K. , Avruch J.
Biochim. Biophys. Acta1542:41-56(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION;INTERACTION WITH MTOR;TISSUE SPECIFICITY
12.

"Role of ubiquilin associated with protein-disulfide isomerase in the endoplasmic reticulum in stress-induced apoptotic cell death."
Ko H.S. , Uehara T. , Nomura Y.
J. Biol. Chem.277:35386-35392(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH P4HB
13.

"Mass spectrometric characterization of the affinity-purified human 26S proteasome complex."
Wang X. , Chen C.-F. , Baker P.R. , Chen P.-L. , Kaiser P. , Huang L.
Biochemistry46:3553-3565(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic kidney.
14.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
15.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
16.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
17.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
18.

"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
19.

"The TREX1 C-terminal region controls cellular localization through ubiquitination."
Orebaugh C.D. , Fye J.M. , Harvey S. , Hollis T. , Wilkinson J.C. , Perrino F.W.
J. Biol. Chem.288:28881-28892(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TREX1;SUBCELLULAR LOCATION
20.

"Affinity makes the difference: nonselective interaction of the UBA domain of Ubiquilin-1 with monomeric ubiquitin and polyubiquitin chains."
Zhang D. , Raasi S. , Fushman D.
J. Mol. Biol.377:162-180(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 541-586 ALONE AND IN COMPLEX WITH UBIQUITIN

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